Role of Panchamrit Parpati in Grahani

Abstract

Grahani is a common gastrointestinal disorder affecting a large proportion of the population,

primarily resulting from incorrect dietary habits, sedentary lifestyle and mental stress. In

India, its prevalence shows a female-to-male ratio of 1:3, with the most commonly affected

age group being 20–40 years. In Ayurveda, the pathology of Grahani revolves around

impaired digestive fire (Agni). Acharya Charaka describes Grahani as the primary site of

Agni; therefore, any factor that weakens or vitiates Agni leads to dysfunction of Grahani,

eventually causing Grahani Roga. In modern medicine, the disease can be

correlated with Irritable Bowel Syndrome (IBS), which also shows altered bowel habits,

disturbed digestion and impaired gut function.

The line of treatment in Ayurveda focuses on Deepana and Pachana therapies to rekindle

Agni, eliminate Ama (metabolic toxins) and restore normal digestive physiology. Among

several formulations recommended for Grahani, PanchamritParpati is a highly regarded Rasa

Aushadhi. It possesses Deepana and Pachana properties along with Ushna Guna, which help

enhance appetite, promote efficient digestion and improve nutrient assimilation

Among the

five ingredients of Panchamrit Parpati, usually it composed with the ingredient like parad: gandhak: lauha: tamra: abhra in the ratio of 16:8:4:2:1(2) most are hot in potency and exhibit Katu Vipaka,stimulating Agni at the level of Annavaha Srotasand nourishing Pachak Pitta. By restoring the digestive fire, the formulation reduces the formation of Ama and regulates intestinal movements. Additionally, Panchamrit Parpatipacifies Vata Dosha, thus correcting abnormal bowel patterns and converting Atipravritti (excessive bowel movements) intothe Samyak Pravritti (normal stool pattern).